To give some idea of the effect of an Electro-Pneumatic control system on maximum speeds, due to braking distances:-
The trains I work with have a normal service maximum of 140 kph with EP available on all 28 vehicles.
If 3 wagons have the EP isolated, and only have the normal air brake working, then the permitted speed is reduced by 10%.
If more than 3 vehicles have EP isolated, or there is a problem with the control gear for the EP on the loco, then the train may run at 100 kph maximum. In practice, this means you sideline the train as soon as possible, as you start get knock-on delays to other services.
A colleague went over to Red Team as a driver-leader, having spent more than ten years driving Shuttles. As part of his conversion course to driving on a 'real railway', he drove the 'Jumbo Train' from Westbury to Acton, at a maximum speed of less than 80 kph. He called me later to say that even that seemed too fast, as the brakes seemed to take an eternity to apply (as he's an ex-Para, with a colourful command of English, I've paraphrased that last bit...)